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Image Search Results
Journal: DARU Journal of Pharmaceutical Sciences
Article Title: Synthesis, docking and acetylcholinesterase inhibitory assessment of 2-(2-(4-Benzylpiperazin-1-yl)ethyl)isoindoline-1,3-dione derivatives with potential anti-Alzheimer effects
doi: 10.1186/2008-2231-21-47
Figure Lengend Snippet: Design of new donepezil-like analogs based on the phthalimide structure.
Article Snippet: The pdb file of acetylcholinesterase enzyme in complex with
Techniques:
Journal: DARU Journal of Pharmaceutical Sciences
Article Title: Synthesis, docking and acetylcholinesterase inhibitory assessment of 2-(2-(4-Benzylpiperazin-1-yl)ethyl)isoindoline-1,3-dione derivatives with potential anti-Alzheimer effects
doi: 10.1186/2008-2231-21-47
Figure Lengend Snippet: Superimposed structure of compound 4a with donepezil in the active site of AChE. A similar binding mode and interaction like donepezil are observed for compound 4a.
Article Snippet: The pdb file of acetylcholinesterase enzyme in complex with
Techniques: Binding Assay
Journal: DARU Journal of Pharmaceutical Sciences
Article Title: Synthesis, docking and acetylcholinesterase inhibitory assessment of 2-(2-(4-Benzylpiperazin-1-yl)ethyl)isoindoline-1,3-dione derivatives with potential anti-Alzheimer effects
doi: 10.1186/2008-2231-21-47
Figure Lengend Snippet: Results (IC 50 , μM) of in vitro acetylcholinesterase assay of compounds 4a-4l
Article Snippet: The pdb file of acetylcholinesterase enzyme in complex with
Techniques: In Vitro, AChE Assay